Molecular Formula | C3H9ClN2O2 |
Molar Mass | 140.57 |
Melting Point | 185-188°C(lit.) |
Boling Point | 444.7°C at 760 mmHg |
Specific Rotation(α) | 14 º (c=1, H2O) |
Flash Point | 222.8°C |
Vapor Presure | 8.9E-10mmHg at 25°C |
Appearance | Crystals or Crystalline Powder |
Color | Red to purple |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
HS Code | 29241990 |
overview | the existing methods for preparing L-serinamide hydrochloride are generally as follows: in the first step, boc-ser(tbu)-oh is dissolved in THF, N-methyl morphine, ethyl chloroformate and ammonia water are added at -10 ℃ to obtain boc-ser(tbu)-nh2, in the second step, boc-ser(tbu)-nh2 gas is passed through hydrochloric acid to obtain H-Ser-NH2.HCL crude product. In the third step, the H-Ser-NH2.HCL crude product is recrystallized with methanol. This method has harsh synthesis conditions, high price of raw material boc-ser(tbu)-oh, low amidation yield and exposure to toxic substances, which is not conducive to mass production. |